Innate immunity against bacterial pathogens
The innate immune system is the first line in defense against microbial pathogens. We study how host defense proteins recognize and attack bacterial pathogens.
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Our team studies host-pathogen interactions in infectious biology
Bacterial evasion of host defenses
Pathogens and hosts are in a constant tug of war. We study how bacterial pathogens evade innate immune defenses.
Inflammation during bacterial infections
Inflammation is a potent immune defense, but can lead to severe tissue damage and sepsis. We study the mechanisms underlying bacteria-induced inflammation.
Antimicrobial strategies
Antimicrobial resistance of bacterial pathogens is rapidly increasing. We use our understanding of host-pathogen interactions to develop new strategies for combatting multi-drug-resistant bacteria.